THAPCA - Publications

Medical Publications

Topjian AA, Telford R, Holubkov R, Nadkarni VM, Berg RA, Dean JM, Moler FW, Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trial Investigators. "Association of Early Postresuscitation Hypotension With Survival to Discharge After Targeted Temperature Management for Pediatric Out-of-Hospital Cardiac Arrest: Secondary Analysis of a Randomized Clinical Trial." JAMA Pediatr Dec 2017
Slomine BS, Nadkarni VM, Christensen JR, Silverstein FS, Telford R, Topjian A, Koch JD, Sweney J, Fink EL, Mathur M, Holubkov R, Dean JM, Moler FW; THAPCA Trial Investigators. "Pediatric cardiac arrest due to drowning and other respiratory etiologies: Neurobehavioral outcomes in initially comatose children." Resuscitation Jun 2017
Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL,Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM, for the THAPCA Trial Investigators. "Therapuetic Hypothermia after In-hospital Cardiac Arrest in Children" New England Journal of Medicine 24 Jan 2017
Meert KL, Telford R, Holubkov R, Slomine BS, Christensen JR, Dean JM, Moler FW; THAPCA Trial Investigators. "Exploring the safety and efficacy of targeted temperature management amongst infants with out-of-hospital cardiac arrest due to apparent life threatening events" Resuscitation Oct 2016
Meert KL, Telford R, Holubkov R, Slomine BS, Christensen JR, Dean JM, Moler FW; THAPCA Trial Investigators. "Pediatric Out-of-Hospital Cardiac Arrest Characteristics and their Association With Survival and Neurobehavioral Outcome" Pediatric Critical Care Medicine Sep 2016
Moler FW, Hutchison JS, Nadkarni VM, Silverstein FS, Meert KL, Holubkov R, Page K, Somine BS, Christensen JR, Dean JM; THAPCA Trial Investigators. "Targeted Temperature Management After Pediatric Cardiac Arrest Due to Drowning: Outcomes and Complications" Pediatric Critical Care Medicine Aug 2016
Silverstein FS, Slomine BS, Christensen J, Holubkov R, Page K, Dean MJ, Moler FW; THAPCA Trial Investigators. "Functional Outcome Trajectories After Out-of Hospital Pediatric Cardiac Arrest" Critical Care Medicine Aug 2016
Meert KL, Slomine BS, Christensen JR, Telford R, Holubkov R, Dean JM, Moler FW; THAPCA Trial Investigators. "Family Burden After Out-of-Hospital Cardiac Arrest in Children" Pediatric Critical Care Medicine Jun 2016
Slomine BS, Silverstein FS, Christensen JR, Holubkov R, Page K, Dean JM, Moler FW; THAPCA Trial Group. "Neurobehavioral Outcomes in Children After Out-of-Hospital Cardiac Arrest" Pediatrics Apr 2016
Browning B, Page K, Kuhn R, DiLiberto M, Deschenes J, Taillie E, Tomanio E, Holubkov R, Dean JM, Moler FW, Meert KL, Pemberton VL. "Nurses' Attitudes Toward Clinical Research: Experience of the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials" Pediatric Critical Care Medicine March 2016
Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC Jr, Dean JM; THAPCA Trial Investigators. "Therapuetic Hypothermia after Out-of-hospital Cardiac Arrest in Children" New England Journal of Medicine 25 Apr 2015
Holubkov R, Clark A, Moler F, Slomine B, Christensen J, Silverstein F, Meert K, Pollack M, Dean J. "Efficacy outcome selection in the therapeutic hypothermia after pediatric cardiac arrest (THAPCA) randomized trials" Pediatr Crit Care Med 16:1-10, 2015
Moler FW, Silverstein FS, Meert KL, Donaldson AE, Holubkov R, Browning B, Slomine BS, Christensen, JR, Dean JM. "Rationale, Timeline, Study Design and Protocol Overview of the Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trials" Pediatr Critical Care Med 14: e304-15, 2013
Pemberton VL, Browning B, Webster A, Dean JM, and Moler FW. "Therapeutic Hypothermia after Pediatric Cardiac Arrest Trial: The Vanguard Phase Experience and Implications for other Trials" Pediatr Critical Care Med 14:19-26, 2013
Topijian AA, Clark AE, Casper TC, Berger JT, Schleien CL, Dean JM, Moler FW for the Pediatric Emergency Care Applied Research Network. "Early lactate elevations following resuscitation from pediatric cardiac arrest are associated with increased mortality" Pediatric Critical Care Medicine 14:380-7, 2013
Bennett KS, Clark AE, Meert KL, Topijian AA, Schleien CL, Shaffner DH, Dean JM, Moler FW for the Pediatric Emergency Care Applied Research Network. "Early oxygenation and ventilation measurements after pediatric arrest: lack of association with outcome" Critical Care Medicine 41:1534-42, 2013
Moler FW, Donaldson AE, Meert KL, Brilli RJ, Nadkarni V, Shaffner DH, Schleien CL, Clark RSB, Dalton HJ, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Pineda J, Hernan L, Dean JM, for the Pediatric Emergency Care Applied Research Network (PECARN). "Multicenter Cohort Study of Out-of-Hospital Pediatric Cardiac Arrest" Critical Care Med 2011; 39: 141-9
Meert KL, Donaldson A, Nadkarni V, Tieves KS, Schleien CL, Brilli RJ, Clark RSB, Shaffner DH, Levy F, Statler K, Dalton HJ, van der Jagt EW, Hackbarth R, Pretzlaff R, Hernan L, Dean JM, Moler FW for the Pediatric Emergency Care Applied Research Network. "Multicenter Cohort Study of In-Hospital Pediatric Cardiac Arrest." Pediatr Crit Care Med 2009; 10:544-553.
Moler FW, Meert KL, Donaldson AE, Nadkarni V, Brilli RJ, Dalton HJ, Clark RSB, Shaffner DH, Schleien CL, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Levy F, Hernan L, Silverstein FS, Dean JM, for the Pediatric Emergency Care Applied Research Network. "In-hospital versus out-of-hospital pediatric cardiac arrest: A multicenter cohort study" Critical Care Med 2009; 37:2259-2267.